Clinical Studies
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AIDS and the Gastrointestinal Tract
| Principal Investigator: | Donald Kotler, MD | |
| Time frame of study: | Ongoing | |
| Time frame of participation: | N/A | |
| Number of participants needed: | Open | |
| Location of Study: | St. Luke's-Roosevelt Hospital Center |
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| Contact Name, Number & Email: | Dr. Kotler 212-523-3674 |
Summary:
This program evaluates and treats HIV-infected individuals for gastrointestinal and nutritional complications of the disease. Ongoing studies are dissecting the relationships between cellular HIV infection in the intestine, enteric pathogens, oxidative stress, immune depletion and clinical symptoms. Treatment studies are determing the safety and efficacy of experimental antiparasitic and anti-inflammatory agents in AIDS patients. Nutritional studies include analysis of factors controlling protein supplementation, anablolic agents and exercise upon body composition and skeletal muscle structure and function as well as studies of body fat distribution and metabolic disturbances occurring in patients receiving potent antiretroviral agents.